Product Description
Peptide Powder Tb500 Beta-4 5mg/Vial Bodybuilding for Healing Wound
Thymosin Beta 4 is a naturally occurring peptide. It is found in high concentrations in blood platelets, wound fluid and other tissues in the body. Tβ4 is not a growth factor; rather, it is a major actin regulating peptide. Tβ4 has been found to play an important role in protection, regeneration and remodeling of injured or damaged tissues. The gene for Tβ4 has also been found to be one of the first to be upregulated after a wound occurs.
Thymosin beta 4 ameliorates hyperglycemia and improves resistance of KK Cg-Ay/J mouse
resistance is a key feature of type 2 diabetes mellitus and is also associated with an increased risk of cardiovascular disease (CVD) [1-3]. There are lots of drugs in the market which aim to improve insulin resistance. However, besides metformin, other drugs have had serious adverse effects and have either been withdrawn from the market or subjected to serious warnings. For instance, rosiglitazone, an insulin sensitizer which acts by binding to the PPAR receptors in fat cells and making the cells more responsive to , has been found to be associated with an increased risk of heart attack [4]. Thus, it is very necessary to explore novel potential sensitizers which could not only improve the insulin resistance but also decrease the risk of cardiovascular disease
Thymosin Beta 4 (Tβ4) is a major intracellular G-actin-sequestering peptide with amino acid sequence Ac-SDKPDMAEIEKFDKSKLKKTETQEKNPLPSKETIEQEKQAGES. Studies have shown that Tβ4 levels decreased significantly in corneas of diabetic patients compared with healthy subjects, and exogenous Tβ4 administration would promote wound healing in diabetic and nondiabetic corneas. Tβ4 could also improve glucose intolerance and ameliorated resistance in KK mouse, which indicated that Tβ4 may be a potential alternative insulin sensitizer for the treatment of type 2 diabetes mellitus.
For Research Purpose only, Not for Human Consumption
How to use TB-500
TB-500 is typically provided as lyophilized (freeze-dried) powder in vials of 2.0 mg. A convenient amount of sterile or bacteriostatic water will be added, such as 1.0 mL. In the most common dosing protocol, the entire vial is taken at one time. If taking the entire vial, the entire amount will be drawn into a syringe, typically an insulin syringe, and injected. Injection may be subcutaneous, intramuscular, or intravenous, according to personal preference.
The most common dosing protocol is to take 2.0 or 2.5 mg of TB-500 twice per week for four to six weeks, and then reduce to a lower dosing rate such as once or twice per month for maintenance.
The body of knowledge is as yet limited with regard to TB-500 dosage. The above protocol may or may not be the most efficient, but it is the protocol with the most track record. It's entirely possible that as knowledge is gained, method of use will change. A reasonable possibility, for example, is to increase dosing frequency to 3x/week (which I have done personally to good effect), or to increase dosing to 4 or 5 mg twice per week. Before going to such a program, however, I recommend trying the standard protocol first.
If interested in animal uses, a typical dosing protocol for horses is a course of six 10 mg injections at 7-10 day intervals. For more intensive treatment, 20 mg is used weekly. For racing dogs, a typical protocol is a course of six 5 mg injections taken weekly.
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