Muscle Growth SARMS Supplements Andarine S4 / GTX-007 for Bodybuilders
Chemical Name: 4 – ((R) -2 – ((R) -2,2,2-trifluoro-1-hydroxyethyl) pyrrolidin-1-yl) -2-trifluoro-methyl) benzonitrile
Other Name(s): GTX007
Half Life: 2.6 – 5.3 hours
S4 (Andarine) or Acetamidoxolutamide, is a SARM (Selective Androgen Receptor Modulator). But the idea for S-4 didn’t start out as many believe.
It wasn’t an attempt to create a safer version of steroids or any of that nonsense people use to sell anabolics.
S-4 started out as a new development for male contraceptives and showed promising results like decreases in spermatogenesis and huge boosts in male libido. For any of you who have had trouble getting your wife pregnant while on sarms…you’re welcome.
However, when researchers began experimenting on mice with S4, they discovered interesting findings of how this first generation SARM affected castrated lab mice.
Not only did Andarine increase the production of muscle mass and calcium for bone density, but it was COMPLETELY SELECTIVE in its tissue growth!
As studies continued, many of these research trials resulted in astonishing outcomes creating a benchmark for even more research.
Today, we’ll take a closer look at everything we currently know in 2018 about Andarine in this write-up…
HOW ANDARINE (S4) WORKS
To start, let’s describe what a SARM does.
There are three types of chemicals that act on the androgen receptor (AR):
- 1st is the AR antagonist, which is a chemical that binds to the receptor to prevent it from activating.
- 2nd is an AR agonist, which binds to the receptor and detaches, then binds again, over and over.
- 3rd is an AR modulator, or basically a molecule that attaches to an AR and changes its structure to react however it wants.
SARMs such as S-4 are a good example. S-4 attaches to the AR and sticks to it; each time the AR interacts with testosterone, S-4 forces it to produce genes that exclusively benefit the muscle and bone growth. In other words, S4 is a form of SARM that attaches to the androgen receptor (AR) the same with regular androgens, the only variation is that S4 generates selective anabolic activity.
As mentioned earlier, SARMS function by tying to the AR resulting in anabolic activity. Due to this fastening and stimulation, more protein is produced which allows muscle building. S4 can trigger muscle development in the same way as steroids, but minus the same unwanted side effects.
S4 is a SARM with utmost androgenic effects and is 33% of the strength of testosterone when attaching to AR.
S-4 also increases the amount of muscle mass produced by desensitizing the AR to the individual’s natural testosterone to influence a stronger effect.