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Mechano Growth Factor 2mg Peptide Hormones Bodybuilding MGF Powder 100 % Delivery

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Mechano Growth Factor 2mg Peptide Hormones Bodybuilding MGF Powder 100 % Delivery

China Mechano Growth Factor 2mg Peptide Hormones Bodybuilding MGF Powder 100 % Delivery supplier

Large Image :  Mechano Growth Factor 2mg Peptide Hormones Bodybuilding MGF Powder 100 % Delivery

Product Details:

Place of Origin: China
Model Number: N/A

Payment & Shipping Terms:

Minimum Order Quantity: 1 kit
Price: Nedotiation
Packaging Details: 10 Vials/Kit, Aluminum foil+bubble+paper box
Delivery Time: 1-2 working days
Payment Terms: Western Union, T/T, MoneyGram, Aliexpress
Supply Ability: 2000kits/month
Detailed Product Description
Product Name: MGF, Mechano Growth Factor Purity: >98%
Specification: 2mg Storage: 2-8 Degree Centigrade Refrigerator
Sequence: Tyr-Gln-Pro-Pro-Ser-Thr-Asn-Lys-Asn-Thr-Lys-Ser-Gln-Arg-Arg-Lys-Gly-Ser-Thr-Phe-Glu-Glu-Arg-Lys Molecular Formula: C121H200N42O39
Synonyms: Mechano Growth Factor, IGF-1 Ec

Mechano Growth Factor 2mg MGF Powder 100% Delivery Peptide Hormone

 

 

Mechano growth factor (MGF) is a novel splice variant of the Insulin-Like Growth Factor-1 (IGF-1), also known as IGF-1 Ec in humans and IGF-1Eb in rodents. It is actually originally called MGF because the RNA form of it is expressed in muscle tissues in response to the overload or/and damage of muscle growth tissue. The C-terminal peptide of the mechano growth factor (MGF) is a crucial region for the alternative splicing of the peptide. The alternative splicing in the MGF is brought about by the shift in the reading frame in which a specific C-terminal sequence (E-domain) is encoded by exon 5 and the first part of the exon 6. Another interesting point in MGF is that, because of the E domain it contains, MGF can act on muscles independently from the rest of the molecule. Furthermore, MGF can elicit very different effects with mGF promoting satellite cells proliferation and IGF-1 inducing differentiation (Dluzniewska et al. 2005).

 

The physiological role of MGF has been well studied on the cellular model in vitro and in mice. In contrast to IGF-1 growth factor causes mechanical mainly division dormant muscle cells by activation of different receptors. Reduced synthesis MGF - this is the main reason that results in the reduction of muscle mass in dystrophic patients and the elderly.

 

Product name MGF, Mechano Growth Factor
Specification 2mg/vial
Appearance White powder
Form & Formulations Sterile Filtered white lyophilized (Freeze-Dried)
Purity >98% by RP-HPLC
Water Content ≤ 7.0% by Karl Fischer
Acetate Content ≤ 10.0% by RP-HPLC
Bacterial Endotoxins ≤ 5EU/mg
Storage 2-8 degree centigrade refrigerator
Pacakge 1kit=10vials Alumnium foil+bubble+carton
 

Age Related Muscle Loss and MGF

MGF was suggested to play a number of physiological roles because the failure in its expression may result to age-related loss of skeletal function. Included in its functions is its ability to become a potent neuroprotective as supported by the study that has shown functional copies of the MGF cDNA to be expressed in a plasmid vector which then protected facial neurons after nerve damage (Dluzniewska et al. 2005). One such failure is called sarcopenia. It would also appear that with regards to age, the young have a better ability to respond to MGF (4), and that the elderly experience a decreased response to MGF which results in a decreased ability to stimulate the growth of new muscle tissue.

How does Mechano Growth Factor work? - Muscle Growth!

When mechanical overload is introduced to a muscle (as by weight training), the IGF-1 gene is released and is differentially spliced during the bodies response. Initially, it it is spliced to produce predominantly IGF-1Ec (called the MGF splice variant of IGF-1). This early splicing stimulates satellite cells into activation. Which in turn allows the activation of extra undamaged nuclei to grow new muscle fiber and tissue. The appearance of MGF also initiates the upregulation of new protein synthesis. After this initial splicing of IGF-1 into MGF, production then switches towards producing a systemic release of IGF-1Ea from the liver, which also upregulates protein synthesis as well. The expression of IGF-1 splice variants, over the course of the healing and regrowth phase of muscle repair is thought to be the primary mechanism by which the body produces new muscle tissue.

 

Mechano Growth Factor 2mg Peptide Hormones Bodybuilding MGF Powder 100 % Delivery

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